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  • Rational approaches, SARS-CoV-2/ACE2 PPI inhibitors

    Rational approaches,
    SARS-CoV-2/ACE2 PPI inhibitors

    Read more

  • Drug repurposing approach, FDA approved drugs against RdRp and 3CLpro.

    Drug repurposing approach,
    FDA approved drugs against RdRp and 3CLpro.

    Read more

  • Structure-based virtual screening & MD,new inhibitors of Staphylococcus aureus sortase A

    Structure-based virtual screening & MD,
    new inhibitors of Staphylococcus aureus sortase A

  • Unveiling diagnostic and therapeutic strategies for cervical cancer: biomarker discovery through proteomics approaches ...

    Unveiling diagnostic and therapeutic strategies for cervical cancer:
    biomarker discovery through proteomics approaches ...

  • Transcriptomic analysis of papillary thyroid cancer: potential biomarkers associated with tumor progression

    Transcriptomic analysis of papillary thyroid cancer:
    potential biomarkers associated with tumor progression

  • Co-expressional conservation in virulence and stress related genes of three Gammaproteobacterial species ...

    Co-expressional conservation in virulence and stress related genes of three Gammaproteobacterial species ...

  • project Protein Modeling
  • project Molecular Docking
  • project Binding interaction analysis

  • Protein Modeling

    The 3D structure of the X was predicted using I-TASSER server and Structure of Kiss 1 receptor protein was obtained from SWISS-MODEL.

  • Molecular Docking

    Molecular docking of the X and Kiss 1 receptor protein was performed using HDOCK server.

  • Binding interaction analysis

    The X- Kiss 1 receptor protein complex obtained from HDOCK server were opened in Discovery Studio Visualizer. The docked poses were visually inspected to identify Key Interactions between the two proteins.

  • Chimera, Molegro Investigation of interactions between drug and mutated protein
  • Vina, Discovery Studio Docking and 2D interaction analysis
  • RMSD, RMSF, Rg, SASA MD and MMPBSA

  • Investigation of interactions between drug and mutated protein

    Client request for molecular docking, molecular dynamics and MMPBSA analysis services

  • Docking and 2D interaction analysis

    performing molecular docking between inhibitors and protein X and visualize 2D interaction

  • MD and MMPBSA

    Perform 200ns molecular dynamics simulation and MMPBSA analysis.

  • Client project Nanostructures
  • Client project Docking
  • Client project Results

  • Nanostructures

    The aim of this study was to investigate the interactions between Hemoglobin and the nanostructures with using AutoDock Vina. The AutoDock Vina software was used for the docking simulations because it is a widely used tool for molecular docking and is known for its accuracy and speed.

  • Docking

    The docking simulations were performed using the AutoDock Vina software. The docking box was centered on the protein structure, covering the entire protein. The grid box size was set to 80 x 70 x 80 Angstroms with a spacing of 1 Angstrom between grid points.

  • Results

    The docking results were analyzed using AutoDock Tools. The binding energy and other parameters such as hydrogen bonds, electrostatic interactions, and van der Waals interactions were analyzed using Discovery Studio.

  • RNA-Seq Differential Expression of mRNAs in ***
  • Venn Differential Expression of mRNAs in ***
  • heatmap Differential Expression of mRNAs in ***
  • GO Differential Expression of mRNAs in ***
  • Kegg Differential Expression of mRNAs in ***

  • Differential Expression of mRNAs in ***

    • Alignment and Mapping with STAR
    • Differential Expression Analysis
    • Gene Ontology (GO) Analysis
    • Pathway Enrichment Analysis

  • Differential Expression of mRNAs in ***

    • Alignment and Mapping with STAR
    • Differential Expression Analysis
    • Gene Ontology (GO) Analysis
    • Pathway Enrichment Analysis

  • Differential Expression of mRNAs in ***

    • Alignment and Mapping with STAR
    • Differential Expression Analysis
    • Gene Ontology (GO) Analysis
    • Pathway Enrichment Analysis

  • Differential Expression of mRNAs in ***

    • Alignment and Mapping with STAR
    • Differential Expression Analysis
    • Gene Ontology (GO) Analysis
    • Pathway Enrichment Analysis

  • Differential Expression of mRNAs in ***

    • Alignment and Mapping with STAR
    • Differential Expression Analysis
    • Gene Ontology (GO) Analysis
    • Pathway Enrichment Analysis

This is the beginning

Ongoing projects

We believe in transparency and accountability, which is why we provide a progress report for each of our ongoing projects. This helps our clients stay informed about the status of their projects and ensures that we are meeting their expectations!

Differential Expression Analysis of Long Noncoding RNAs in ...

90%

Molecular docking and Dynamics of antifreeze peptide and protein X

45%

Molecular docking and Dynamics of ligand X and protein transferrin

25%

Completed Projects

Drug reproposing of SARS Covid 19 Spike protein

100%

Virtual screening of in-house library with protein X

100%

Docking of 7 azo dyes with protein X

100%

200 ns Molecular Dynamics Simulation of protein X - M10** peptide complex

100%

MMPBSA Analysis of protein X - M10** peptide complex

100%

Molecular docking and dynamics Simulation of protein X - Au nanoparticle

100%

Cross docking of 20 proteins and FDA approved drugs

100%

Binding interaction analysis of HT-hTS with ligand X

100%

and more than 100 completed projects ...

This is not the end

More Works

Here, you can explore our company’s works. We’ve compiled a collection of our most exciting and innovative projects to showcase the breadth and depth of our expertise in these fields. Take a look around and discover what we’ve been up to!

Genomics

Genomics

Proteomics

Proteomics

Drug Design

Drug Design

Vaccine Design

Vaccine Design

Docking

Docking

Metagenomics

Metagenomics

Scientific Illustrations

Scientific Illustrations

Review Article

Review Article

Molecular Dynamics

Molecular Dynamics